01
Mitochondria
The cellular machinery involved in producing usable energy changes over time.
NOVOS Energy: cellular, physical and sustained energy support
Energy + healthy aging
More than a boost.
Energy starts deeper than you feel.
Most "energy" products start with a stimulant. NOVOS starts with the biology underneath energy.
Support cellular energy, physical performance, steady focus, recovery and daily nutrition, without building your routine around caffeine or sugar spikes.
- Clinically studied
- Recommended by 2,000+ verified clinicians
- 15M+ NOVOS servings enjoyed worldwide
- Third-party tested
- Mayo Clinic Store
- Equinox
- Erewhon
Energy isn't one thing
Which kind of energy do you mean?
The energy you feel is the result of multiple systems working together: your cells producing ATP, your muscles performing, your brain maintaining focus, your circulation delivering fuel, and your body recovering well enough to do it again tomorrow.
NOVOS supports energy at multiple levels.
Mitochondria illuminate.
Different forms of energy require different biological systems. That's why NOVOS doesn't treat energy as one pathway.
Normal aging
Why energy can feel different with age.
Many people notice that maintaining energy becomes less effortless over time. That does not necessarily mean something is wrong.
Several systems involved in producing and sustaining energy can change with age.
02
NAD+ biology
NAD+ metabolism changes with age, influencing pathways involved in energy metabolism and cellular maintenance.
03
Circulation
Blood-vessel function can change, affecting how efficiently oxygen and nutrients are delivered throughout the body.
04
Muscle
Maintaining muscle and physical capacity becomes increasingly important.
05
Recovery
Sleep quality, stress and recovery can have a larger effect on how ready you feel the following day.
06
Metabolic flexibility
The body's ability to manage and use nutrients efficiently remains important to sustained energy.
The goal isn't to feel artificially stimulated. It's to preserve more of your natural capacity to produce, use and recover energy.
The product system
Three products. Three different energy jobs.
NOVOSCore
Coordinate the system
- Circulation
- Cellular metabolism
- Calm focus
- Stress resilience
- Recovery
NOVOSBoost
Support cellular energy
- NMN
- NAD+
- Cellular metabolism
- Cellular maintenance
NOVOSBar
Supply the fuel
- Protein
- Fiber
- Healthy fats
- Micronutrients
- Functional mushrooms
- Longevity ingredients
These are complementary, not interchangeable.
Whole-system energy
NOVOS Core
Support energy at the source.
Most energy products target a sensation, usually with caffeine, sugar, or another stimulant. NOVOS Core takes a different approach.
It combines longevity ingredients selected to support several systems involved in how energetic you feel: fuel delivery, cellular energy, mental stamina, stress resilience, and sleep and recovery. And it does so without caffeine or stimulants.
Fuel delivery
Healthy circulation helps deliver oxygen and nutrients to active tissues.
Relevant Core ingredients
- Ginger
- Pterostilbene
- Vitamin C
Core · fuel delivery
Energy starts with delivery.
Muscle and brain cells cannot use nutrients and oxygen they never receive. Healthy vascular function helps move blood, oxygen and nutrients throughout the body.
NOVOS Core's finished formulation has been evaluated in a randomized, double-blind, placebo-controlled human clinical trial in adults over 40. Researchers observed benefits versus placebo in validated measures of cardiovascular aging including endothelial function, arterial flexibility and maintenance of healthy blood pressure already within the normal range.
Core · cellular energy
Turn fuel into something cells can use.
- Food
- Cell
- Mitochondria
- ATP
Cells extract usable energy from nutrients through a sequence of biochemical reactions. Malate participates in this energy-producing machinery.
Magnesium Malate
Essential machinery for energy metabolism
Magnesium is required for normal energy-yielding metabolism and normal muscle and nervous-system function.
ATP, the molecule cells use as their immediate energy currency, normally functions in association with magnesium. Malate is also involved in biochemical pathways connected to mitochondrial energy metabolism.
Position: Foundational cellular-energy biology
Malate
Part of the cellular energy cycle.
Cells extract usable energy from nutrients through a sequence of biochemical reactions. Malate participates in this energy-producing machinery.
- What was studied?
- The role of magnesium in energy-yielding metabolism, muscle and nervous-system function.
- In whom?
- Established human nutritional physiology.
- What did research find?
- Magnesium is required for normal energy metabolism, and ATP normally functions bound to magnesium.
- What does it not prove?
- That magnesium acts as a stimulant or produces an immediate felt lift.
Ca-AKG
Where energy metabolism meets aging biology
Alpha-ketoglutarate is a naturally occurring metabolite involved in the cellular energy cycle.
It also participates in signaling and biochemical processes beyond ATP production, which is why it has attracted substantial interest in longevity research. The direct human evidence for Ca-AKG as an energy enhancer is limited.
Position: Cellular metabolism + longevity biology
- What was studied?
- Alpha-ketoglutarate in cellular energy metabolism and aging-related signaling.
- In whom?
- Mostly laboratory and animal models, with early human interest.
- What did research find?
- A well-described metabolic role, plus signaling functions of interest to longevity researchers.
- What does it not prove?
- That Ca-AKG increases subjective energy in people.
Rhodiola rosea
Energy under pressure
Sometimes low energy is not a shortage of calories. It is what happens when physical or mental stress makes maintaining performance harder.
Rhodiola is an adaptogenic plant studied in humans for fatigue, mental performance, physical performance and stress resilience. Some trials report benefits, while systematic reviews note that results and study quality have been inconsistent.
Position: Supporting resilience to fatigue and stress, not a stimulant
- What was studied?
- Rhodiola for fatigue, mental and physical performance, and stress resilience.
- In whom?
- Adults in randomized and controlled human trials.
- What did research find?
- Some trials report benefits for fatigue and performance under load.
- What does it not prove?
- Consistent, high-certainty benefit, since reviews note mixed results and variable study quality.
L-Theanine
Clear energy doesn't have to feel wired
A person can be highly stimulated and still not be productive.
L-theanine has been studied in randomized human research for attention, reaction time and subjective calm. Its relevance to energy is primarily cognitive energy: the ability to stay alert, attentive and mentally steady without relying on overstimulation.
Position: Calm focus
- What was studied?
- L-theanine for attention, reaction time and subjective calm.
- In whom?
- Healthy adults in randomized trials.
- What did research find?
- Measures of attention and calm improved in a number of randomized studies.
- What does it not prove?
- That L-theanine literally suppresses neural noise, or that it replaces sleep or nutrition.
Glycine
Tomorrow's energy starts tonight
Energy and recovery cannot really be separated.
Glycine has human research relating to sleep quality and next-day fatigue and alertness. That makes its Core energy story indirect but highly intuitive: better recovery leads to better readiness.
Position: Recovery energy
- What was studied?
- Glycine before sleep, with sleep quality and next-day fatigue and alertness as outcomes.
- In whom?
- Adults, including people with restricted or poor-quality sleep.
- What did research find?
- Reported improvements in sleep quality measures and next-day fatigue or alertness.
- What does it not prove?
- That glycine itself directly produces energy.
Rhodiola · conceptual view
35%
Conceptual illustration, not clinical data.
Ginger
Relevant to metabolic and circulatory biology.
Supporting pathway
Pterostilbene
Studied for cellular metabolism, oxidative stress and healthy-aging pathways. Direct human energy evidence is limited.
Healthy-aging support
Fisetin
Studied in cellular senescence and other aging-related processes.
Long-term aging biology
Vitamin C
Essential nutrient involved in antioxidant defense and normal physiology.
Foundational support
Not every Core ingredient carries an energy claim. Naming the difference is what makes the primary ingredients meaningful.
The Core experience
What energy feels like matters too.
81%
of NOVOS customers report feeling a difference within two weeks across six areas of wellbeing, including energy.
Self-reported customer survey. The 81% figure reflects any reported change across six wellbeing areas and does not mean 81% reported increased energy. Individual results vary.
"My energy is steadier through the whole day instead of dropping off after lunch. No jittery feeling at all."
Maren HollowayAge 42 · Verified customer
Individual results may vary.
Typical energy product
- Input
- Caffeine / sugar / stimulant
- Feeling
- Rapid stimulation
- Purpose
- Short-term effect
NOVOS Core
- Systems
- Circulation · Cellular metabolism · Nervous-system balance · Recovery · Healthy-aging biology
- Purpose
- Support the underlying systems involved in consistent energy.
Stimulation and energy are not the same thing.
Cellular energy
NOVOS Boost
Go directly to NAD+.
If Core supports the broader biological system behind energy, Boost focuses on one of cellular energy's most important molecules: NAD+.
NAD+ is essential to the biochemical reactions cells use to convert nutrients into usable energy. It also participates in cellular maintenance, DNA-related processes and metabolic signaling.
NOVOS Boost provides NMN, a direct precursor the body can use to produce NAD+.
Cellular energy has an aging story.
NAD+ metabolism changes with age. That matters because NAD+ participates in several processes at once.
Cellular energy
Turning nutrients into usable cellular energy.
Mitochondrial function
Supporting metabolic reactions required for cellular work.
DNA maintenance
Serving enzymes involved in cellular maintenance.
Metabolic health
Participating in nutrient-sensing and metabolic pathways.
Healthy aging
Supporting NAD+-dependent cellular processes that researchers continue studying in aging biology.
NMN has moved beyond animal studies.
Published randomized human studies have investigated NMN for blood NAD+ and NAD-related metabolites, walking ability and physical function, skeletal-muscle metabolism, sleep, daytime drowsiness and fatigue-related outcomes.
Some trials have produced encouraging results. The broader evidence base is still developing, and not every physical-performance endpoint has improved in every study.
These are studies of NMN ingredients and formulations, not clinical trials of finished NOVOS Boost.
- What was studied?
- NMN supplementation with NAD+ metabolites, physical function, muscle metabolism and sleep or daytime function as outcomes.
- In whom?
- Adults, including middle-aged and older participants, in randomized trials.
- What did research find?
- Increases in blood NAD+ or related metabolites, with encouraging results on selected functional outcomes.
- What does it not prove?
- That finished NOVOS Boost improves energy or exercise performance in a clinical trial.
Common misconception
Does more NAD+ feel like caffeine?
No.
NAD+ biology is not the same as central-nervous-system stimulation. NOVOS Boost contains no caffeine.
Supporting NAD+ is about giving cells a precursor involved in fundamental energy metabolism rather than creating an immediate stimulant sensation.
Some NOVOS Boost customers report noticing more energy, while others may not perceive an acute effect. Individual responses vary.
- "Subtle, but my afternoons are less flat."
- "Less fatigue over a few weeks rather than a sudden change."
Verified customers · Individual results may vary.
Broad system. Focused pathway.
Core
The broad energy foundation
- Circulation
- Stress resilience
- Cellular metabolism
- Recovery
- Calm focus
- All 12 Hallmarks of Aging
Boost
Focused NAD+ support
- NMN
- NAD+
- Cellular energy metabolism
- Cellular maintenance
Core + Boost · complementary longevity support
Core supports the broader system. Boost goes deeper on NAD+.
Energy you can eat
NOVOS Bar
Cells still need fuel.
Supplements can support biological pathways. But your body still needs food.
NOVOS Bar brings the energy conversation back to nutrition: complete protein, fiber, healthy fats, carbohydrates, 21 essential vitamins and minerals, functional mushrooms and longevity-focused ingredients.
This is energy you can actually eat.
Lasting fuel, not a sugar rush.
Many convenience snacks are designed around rapidly available carbohydrate and added sugar. NOVOS Bar is built differently.
Each bar combines 15 g complete plant protein, 6 to 7 g fiber, seed butters and organic olive oil, 21 essential vitamins and minerals, five built-in longevity supplements, and only a small amount of sugar in the current applicable formulations.
This combination is designed to be satisfying and provide more complete, balanced nutrition than a typical sugary snack.
- Balanced nutrition instead of a sugar bomb
- Built for steadier energy
- Protein + fiber + fats + micronutrients, not just quick sugar
What's powering the Bar?
Fuel
- Protein
- Carbohydrates
- Healthy fats
Satiety
- Protein
- Fiber
- Seed butters
Micronutrients
- 21 vitamins + minerals
Functional energy
- Cordyceps
- Taurine
- Lion's Mane
- Reishi
- Astaxanthin
Cordyceps
The mushroom with an endurance story.
Cordyceps mushrooms have been studied in humans for aerobic capacity, endurance and exercise performance.
Recent reviews of the human literature suggest potential improvements in selected measures such as endurance performance, time to exhaustion, ventilatory threshold and VO₂-related measures. But results across studies remain inconsistent, and preparations vary substantially.
Position: PROMISING HUMAN EVIDENCE FOR ENDURANCE AND PHYSICAL PERFORMANCE
CordycepsO₂MuscleMovement
- What was studied?
- Cordyceps preparations with exercise and aerobic outcomes.
- In whom?
- Healthy and active adults in exercise studies.
- What did research find?
- Endurance, aerobic fitness, VO₂-related measurements and time to exhaustion improved in selected studies.
- What does it not prove?
- That NOVOS Bar itself improves VO₂max or endurance.
Taurine
Built into muscle and energy biology.
Taurine is naturally abundant in metabolically active tissues including muscle. It participates in biological processes involving calcium handling, cell hydration, mitochondrial biology, muscle function and antioxidant defense.
Human exercise research has also investigated taurine for endurance, power and exercise performance. Recent meta-analytic evidence suggests a possible modest ergogenic effect, though certainty remains limited and results vary by exercise context.
Position: MUSCLE + CELLULAR SUPPORT WITH PROMISING EXERCISE EVIDENCE
- What was studied?
- Taurine with endurance, power and exercise performance outcomes.
- In whom?
- Trained and untrained adults across exercise contexts.
- What did research find?
- Pooled analyses suggest a possible modest performance benefit.
- What does it not prove?
- A reliable effect in every exercise context, or that taurine acts as a stimulant.
Astaxanthin
Energy is partly about recovery.
Astaxanthin is a carotenoid studied for antioxidant biology and exercise recovery.
Randomized human studies and recent meta-analyses have investigated exercise performance, fatigue, oxidative stress, muscle-damage biomarkers and recovery. The newest pooled evidence is more convincing for selected recovery markers than for direct improvements in VO₂max or performance.
Position: SUPPORTING RECOVERY FROM PHYSICAL STRESS
- What was studied?
- Astaxanthin with exercise, fatigue, oxidative stress and recovery outcomes.
- In whom?
- Adults, including trained participants, in randomized trials.
- What did research find?
- More consistent effects on selected recovery and oxidative-stress markers.
- What does it not prove?
- That astaxanthin reliably improves VO₂max or acts as an ergogenic aid.
Lion's Mane
Physical energy isn't much use if your brain checks out.
Lion's Mane has early randomized human research involving attention, reaction time, stress and cognitive performance.
On this page, position it as support for mental energy and clarity rather than physical endurance.
Position: MENTAL ENERGY + CLARITY
- What was studied?
- Lion's Mane with attention, reaction time, stress and cognition outcomes.
- In whom?
- Adults in early randomized trials.
- What did research find?
- Early signals on attention, reaction time and subjective stress.
- What does it not prove?
- Established, replicated cognitive benefit from the finished NOVOS Bar.
Reishi
Resilience matters too.
Reishi has been studied in areas including wellbeing, fatigue, immune biology and physiological stress.
Direct evidence for an acute energy-enhancing effect in healthy adults is limited. Its place in Bar is better framed around resilience, recovery and whole-body support.
Position: RESILIENCE + RECOVERY + WHOLE-BODY SUPPORT
- What was studied?
- Reishi with wellbeing, fatigue, immune and stress-related outcomes.
- In whom?
- Adults, including clinical populations in some studies.
- What did research find?
- Reported effects on wellbeing and fatigue measures in selected studies.
- What does it not prove?
- An acute energy-enhancing effect in healthy adults.
Energy depends on vitamins and minerals before it depends on "energy supplements."
Cells require micronutrients to carry out the biochemical reactions that release energy from food.
NOVOS Bar provides 21 essential vitamins and minerals at 50% of Daily Value each, according to the current product specification. Particularly relevant are nutrients involved in normal energy-yielding metabolism, red blood cell formation, oxygen transport, nervous-system function and normal muscle function.
- B1
- B2
- B3
- B5
- B6
- B12
B vitamins don't contain energy.
They help your body perform the chemistry required to extract and use energy from food.
Micronutrient support matters most where intake is inadequate. Additional B vitamins are not expected to add energy in someone already nutritionally sufficient.
Protein
Supports muscle and provides essential amino acids.
Fiber
Supports satiety, digestion and the gut ecosystem.
Complete nutrition
Fats
Provide energy and help make the Bar satisfying.
Carbohydrate
Provides readily usable dietary energy without making the formulation primarily a high-sugar snack.
A satisfying snack should do more than make hunger disappear for 20 minutes. Protein, fiber and fats slow the experience down and make NOVOS Bar a more substantial nutritional choice than a typical sweet snack.
When energy matters
Between meetings
Nutrition that supports the rest of the day.
NOVOS Bar
Complete nutrition and functional ingredients for the hours when you actually need fuel.
The energy matrix
Match the product to the energy.
What kind of energy are you looking for?
This selector is a general product guide, not medical personalization, and nothing you select is stored.
More stimulation?
Or better support?
- Cellular energy
- Nutrition
- Circulation
- Focus
- Recovery
NOVOS is designed around the systems underneath energy, not simply making you feel more stimulated.
Conceptual illustration.
Transparency
What has actually been studied?
NOVOS Core
Full Formula Human Research
- Human randomized placebo-controlled trial
- Studied: cardiovascular aging markers
- Not directly studied as a primary endpoint: subjective energy, athletic performance
- Also: customer survey, where energy was one of six self-reported wellbeing categories
NOVOS Boost
Formula's molecule in human research
- NMN studied in humans for NAD+ metabolites
- Physical function
- Skeletal-muscle metabolism
- Sleep / daytime function
- Finished NOVOS Boost has not itself been demonstrated in an RCT to improve energy
NOVOS Bar
Ingredient-level human research
- Cordyceps and exercise outcomes
- Taurine and exercise performance
- Astaxanthin and recovery
- Lion's Mane and cognition
- These studies evaluated ingredients or other preparations, not finished NOVOS Bar
This page does not discuss study ingredient dosages or compare research amounts with NOVOS amounts. Product nutrition quantities are shown where they are a central consumer fact.
Energy isn't:
Jitters
Feeling stimulated is not the same as producing more cellular energy.
Sugar
Calories provide energy, but a high-sugar snack is not the only way to fuel the body.
Motivation
Feeling motivated and having biological energy are related experiences, but not identical.
Never feeling tired
Fatigue after genuine exertion is normal.
One molecule
Even NAD+ is only one part of a much larger energy system.
Energy is a network.
Core supports the broad system. Boost supports the cellular pathway. Bar supplies nutritional fuel.
Products are one part of your energy system.
Sleep, movement, fitness, diet, stress and medical health all influence energy. For the broader lifestyle framework, explore the NOVOS Routine.
Choose where to support your energy.
NOVOS Core
Support the whole system.
- Cellular metabolism
- Circulation
- Calm focus
- Stress resilience
- Recovery
Best starting point for broad daily energy support
Explore Core →NOVOS Boost
Go deeper on cellular energy.
- NMN
- NAD+
- Cellular metabolism
- Cellular maintenance
Best for focused NAD+ support
Explore Boost →NOVOS Bar
Put energy on the menu.
- Complete protein
- Fiber
- Healthy fats
- 21 micronutrients
- Cordyceps
- Taurine
- Functional mushrooms
Best when you need actual nutrition
Explore Bar →Not sure where to start?
FAQ
Energy questions, answered.
Cells convert nutrients into ATP, the immediate energy currency used to power cellular work.
Mitochondria play a central role in this process, while molecules such as NAD+ participate in the underlying metabolic reactions.
No.
NOVOS Core is designed to support biological systems involved in energy, focus and recovery without relying on caffeine or another stimulant.
NOVOS Core's finished formulation has been studied in a randomized placebo-controlled human trial, but the measured endpoints were cardiovascular-aging markers rather than energy or fatigue. Energy support is based on the biological roles and research involving Core ingredients, as well as self-reported customer experiences.
Blood flow delivers oxygen and nutrients to tissues including the brain and muscles.
Core's clinical cardiovascular findings therefore relate to a biological system important to fuel delivery, although they should not be presented as direct proof of increased energy.
Core takes a broad approach, supporting multiple systems relevant to energy including circulation, cellular metabolism, stress resilience, calm focus and recovery.
Boost focuses specifically on NMN and NAD+, a pathway central to cellular energy metabolism and cellular maintenance.
No.
NAD+ metabolism is cellular biology, not stimulant biology. Boost contains no caffeine.
Published randomized human studies have found increases in blood NAD+ or related metabolites after NMN supplementation.
Those findings come from ingredient research rather than finished-product clinical research on NOVOS Boost.
It is better described as a longevity nutrition bar.
It provides complete plant protein, fiber, healthy fats, micronutrients and functional ingredients relevant to energy, exercise, cognition and healthy aging.
NOVOS Bar has not been clinically tested to demonstrate prevention of glucose spikes or crashes. It is formulated with protein, fiber and fats and relatively little sugar, making it a more balanced nutritional approach than a snack built primarily around refined carbohydrate or added sugar.
Cordyceps mushrooms have been investigated in human exercise studies for outcomes including endurance, aerobic capacity and exercise performance.
The evidence is promising but not completely consistent.
Taurine participates in muscle, mitochondrial and cellular biology.
Human exercise trials have also investigated taurine for performance, with recent pooled analyses suggesting a possible modest benefit but remaining uncertainty.
Astaxanthin has been studied in randomized trials for exercise and recovery.
Recent pooled evidence suggests its more consistent role may be in selected recovery biomarkers rather than directly increasing exercise performance.
NOVOS Vital is designed primarily around organ, metabolic, digestive and whole-body support. While those systems certainly contribute to vitality, Core, Boost and Bar have more direct and differentiated energy stories, so this page focuses on them.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.