Ever feel tired… even when you've done everything right?
Energy isn’t just something you feel. It’s something your body has to make. NOVOS Core supports the biological systems tied to energy production, focus, recovery, and long-term health, all in one daily longevity drink.
12 science-backed ingredients. One daily drink. Built for long-term health.
Over 10 million doses served · Recommended by 1,800+ Doctors & Clinicians
SHIPS IN 24–48H · FREE SHIPPING · SECURE CHECKOUT
— Award Winning Formulation —
Join 35,000+ people investing in their longevity
Mayo Clinic, Mayo Clinic Store, Bumrungrad International Hospital, Erewhon, Equinox, The Four Seasons, and Sunlife Organics are trademarks of their respective owners.
*Claims are based on randomized, placebo-controlled human clinical research on the finished NOVOS Core Clinical formulation, along with mechanistic and preclinical studies. In vitro and animal studies are not indicative of impact on humans.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
12 supplements. One drink.
Replace a complicated daily stack with one convenient, great-tasting drink mix — formulated with clinically relevant doses of every ingredient.
Created by Harvard & MIT scientists.
Backed by 7+ years of R&D and a completed randomized, placebo-controlled human clinical trial on the finished formulation.
This isn't another energy supplement
Typical energy products
- Built around a stimulant
- Designed for a short-term lift
- Targets a single pathway
NOVOS Core
- Supports underlying biology
- Supports more consistent energy
- No stimulants; works over time at the foundation
- Multi-pathway formula
Why energy gets harder to sustain
Energy is not just about getting a boost. Your body has to deliver fuel, turn it into usable energy, stay balanced under stress, and recover well enough to do it again tomorrow.
That is why NOVOS Core supports more than one system at once.
Fuel Delivery
Your cells need oxygen and nutrients to keep up with daily demands. Healthy circulation helps support that steady delivery.
Cellular Energy
Your mitochondria help turn nutrients into energy your cells can use. Supporting mitochondrial health helps support steady energy from within.
Recovery
How you feel today is shaped by how well your body recovered yesterday. Sleep, repair, and recovery all help your body feel ready again.
Calm Focus
Energy should not feel jittery or wired. Supporting nervous system balance helps you feel clear, steady, and focused.
NOVOS Core was designed to support these systems together, with 12 science-backed ingredients in one daily drink.
Magnesium
Supports energy metabolism, muscle function, and recovery.
Rhodiola rosea
Supports resilience to fatigue and stress, and energy under physical and mental load.
Glycine
Supports sleep quality and recovery, contributing to more consistent next-day energy.
Calcium Alpha-Ketoglutarate
Involved in cellular energy pathways and metabolic processes associated with energy production.
Malate
Plays a role in mitochondrial energy production and supports cellular energy generation.
L-Theanine
Supports calm focus and helps avoid the overstimulated or wired feeling.
Ginger Extract
Supports circulation and metabolic function, and may support sustained vitality.
Fisetin
A senolytic-class flavonoid studied for its role in supporting cellular cleanup processes associated with aging.
Pterostilbene
A polyphenol studied for support of healthy cellular metabolism and resilience.
Glucosamine Sulfate
Supports joint comfort and cellular signaling pathways associated with aging.
Hyaluronic Acid
Supports skin hydration and connective-tissue resilience.
Vitamin C
Supports antioxidant defense and collagen formation.
How to Use
Mix one sachet daily
Add to 6-8 oz of water, juice, or your morning smoothie.
Stir or shake
Dissolves easily. Available in Orange, Tropical Passion, or Unflavored.
Take consistently
Benefits build over time. Clinical results observed at 6 months of daily use.
Benefits build over time
NOVOS Core works at the level of biology. Benefits build over time — but here's a typical timeline customers describe.
You'll probably feel normal. Some customers report a small uptick in clarity or calm; many feel nothing different yet. That's expected. The work is happening underneath.
Energy starts feeling more even across the day. Afternoon dips ease up. Recovery often improves first.
Many customers describe noticing they "feel more like themselves" — sharper mornings, steadier afternoons, better sleep.
The duration of the clinical trial. The biological systems NOVOS Core supports — circulation, cellular energy, recovery, nervous system — compound with consistent daily use.
Individual results may vary.
Backed by clinical research on key health systems
In a randomized, double-blind, placebo-controlled human clinical trial in adults aged 40+, researchers at the University of Surrey observed statistically significant benefits over placebo across multiple validated markers of vascular aging — including endothelial function, arterial flexibility, and maintenance of healthy blood pressure within the normal range. These vascular systems play a foundational role in how oxygen and nutrients reach your brain, muscles, and cells, and are closely associated with how your energy feels day-to-day.
Trial registered as ClinicalTrials.gov NCT06145087. Senior author: Prof. Christian Heiss, MD, Professor of Cardiovascular Medicine, University of Surrey.
FMD: Blood Circulation
NOVOS Core delivered statistically significant benefits to flow-mediated dilation (FMD) versus placebo — observed during the trial and for an extended time thereafter. Placebo showed no meaningful change.
* p < 0.001 vs. placebo. Data from randomized, double-blind, placebo-controlled trial.
Trial highlights: +3.9% adjusted between-group FMD difference observed 1 hour after the first dose; +2.9% sustained at 6 months (p < 0.0001). Pulse wave velocity improved by 1.18 m/s versus placebo at 6 months. Placebo-adjusted systolic blood pressure difference of −6.1 mmHg, with participants remaining within the normal range throughout. (For blood pressures already in normal range.)
Blood Vessel Flexibility
Beneficial arterial flexibility in healthy adults
Blood Pressure
Beneficial effects on maintenance of healthy blood pressure within the normal range
Cardiovascular Markers
Benefits to aging-related markers
Baseline
40–60+
age-equivalent FMD
With NOVOS
20–30+
age-equivalent FMD
Randomized, placebo-controlled human study in healthy adults aged 40+. Age equivalences are descriptive comparisons of FMD values to published age-stratified reference ranges in healthy populations. This is not a measure of biological age and is not equivalent to results from DunedinPACE or other biological-age tests.
Designed by Scientists and Physicians Studying Aging at Its Core
NOVOS Core was developed in collaboration with leading scientists and physicians whose research focuses on the biology of aging — from Harvard Medical School, MIT, the Salk Institute, USC School of Medicine, and other top institutions.
Rather than targeting just one pathway, the formulation was designed to support multiple biological processes associated with aging, energy, and recovery.
"I see NOVOS as inspiring — they approach aging as a complex phenomenon, aiming at all pathways and hallmarks of aging simultaneously."
Dr. George Church, PhD
Harvard Medical School & MIT Professor
"It's the rigorously-researched, science-backed formulations that set NOVOS apart in the longevity supplements space."
Dr. Robert Lufkin, MD
USC School of Medicine Professor
"What really impressed me about NOVOS was the comprehensiveness of their analysis of aging research to design their product."
Dr. Pamela Maher, PhD
Salk Institute & University of British Columbia
"NOVOS has been using a novel science-based approach for developing its formulation. They are a leader in the longevity space."
Dr. J. Pedro Magalhães, PhD
Harvard Medical School
"The study demonstrates that this multi-ingredient formulation exhibits synergistic effects rarely achieved by a nutritional supplement."
Dr. Satomi Miwa, PhD
Translational Biology of Aging, Newcastle University (commenting on preclinical study results)
What you may notice
Steadier energy from morning through evening
Sharper focus through the afternoon dip
Better recovery after exertion
More restorative sleep
Feeling more "on" more often
Real Customers. Real Energy Improvements.
Experiences vary, but many customers report more consistent energy, sharper focus, and less fatigue.
So much energy
"I don't think I've felt this good since I was a kid - like 6 years old. I have energy from morning to bedtime and sleep reasonably soundly - better than before. Mental focus is the best I've had in most of my life."
Julie G.Verified Customer
Individual results may vary.
A Week to Calmness and Enhanced Endurance
"I have been on this for a week and I'm blown away already. I feel so calm, have sharper clarity of mind, less fatigue and more endurance into the evening hours. I can't imagine being without this."
Beth P.Verified Customer
Individual results may vary.
Seriously impressed
"I've been taking Novos Core for over a year now and I'm seriously impressed with the results. Since I started taking it, I've never felt more energized or focused throughout the day."
Grace D.Verified Customer
Individual results may vary.
Focus and energy
"As far as my experience with the product goes, unless I'm deceiving myself, my focus has sharpened and my energy level has markedly improved. In general I feel more optimistic."
Phillip S.Verified Customer
Individual results may vary.
Love it
"I've taken this only for few months now but I already feel less tired and having more energy throughout the day."
Paul W.Verified Customer
Individual results may vary.
Feel better now. Invest in your long-term health.
NOVOS Core supports systems associated with aging, recovery, and vitality over time. The same pathways that help you feel more energized today play a role in how well your body performs as it ages.
This isn't about a quick fix. It's about building a foundation for how you want to feel — now and in the years ahead.
HSA/FSA eligible — customers save an average of 30% on orders.
Support Your Energy at the Source
Subscriptions
Every subscription includes the NOVOS Life app — your healthspan protocol, tracked daily.
Choose from 3 tasty flavors
Secure checkout · Ships in 24-48h · Free Shipping
Common questions
Energy you can feel. Science you can trust.
Support the biological systems behind your energy, recovery, and long-term vitality.
Support Your Energy at the SourceRecommended by 1,800+ Doctors & Clinicians